rhIGF-1 Therapy: A Silver Bullet for Bronchopulmonary Dysplasia Prevention?
نویسندگان
چکیده
منابع مشابه
Melatonin Supplementation as Adjuvant Therapy for the Prevention of Bronchopulmonary Dysplasia in Neonates
Background: Neonatal bronchopulmonary dysplasia (BPD) is a chronic chest disease caused by prolonged ventilation and oxygenation which leads to neonatal disability.Methods: It was a prospective randomized clinical trial (RCT) (Study ID: TCTR20191211004) which was conducted in Tanta University Hospital (TUH) from July 2016 to March 2018 on 100 preterm neonates who exhibited severe respirat...
متن کاملDrug therapy for the prevention and treatment of bronchopulmonary dysplasia
INTRODUCTION As more infants are surviving at younger gestational ages, bronchopulmonary dysplasia (BPD) remains as a frequent neonatal complication occurring after preterm birth. The multifactorial nature of the disease process makes BPD a challenging condition to treat. While multiple pharmacologic therapies have been investigated over the past two decades, there have been limited advances in...
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Bronchopulmonary dysplasia (BPD) remains the most common pulmonary cause of mortality and long-term morbidity in preterm infants. The two major pharmacologic advances in perinatal medicine have been antenatal corticosteroids to decrease the incidence of respiratory distress syndrome (RDS) (1) and surfactant to treat RDS (2). However, both therapies increase the survival of the most fragile extr...
متن کاملPerinatal prevention of bronchopulmonary dysplasia.
Bronchopulmonary dysplasia (BPD), defined as oxygen dependency for at least 28 days after birth, is a common adverse outcome of very premature birth. Affected children require frequent readmissions to hospital in the fi rst 2 years, and although lung growth and remodelling results in progressive improvement in lung function, airflow abnormalities may remain. Indeed, the most severely affected e...
متن کاملComparing the Efficacy of High and Low Doses of Vitamin A in Prevention of Bronchopulmonary Dysplasia
Background Bronchopulmonary dysplasia (BPD) is one of the most common serious squeal of preterm infants. It involves approximately one quarter of infants with birth weight less than 1500 grams and 30% of less than 1000 grams. Vitamin A has been shown to reduce BPD rate. We compared efficacy of low and high doses of vitamin A for prevention of BPD in very low birth weight preterm infants. Materi...
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ژورنال
عنوان ژورنال: American Journal of Respiratory and Critical Care Medicine
سال: 2020
ISSN: 1073-449X,1535-4970
DOI: 10.1164/rccm.202002-0287ed